CommentStreams:Db8eddffde4ff32eb215137f2cb528bb

As Wanderer2020 said, it's not a matter of "if" you can win against bosses (chapter 80 is a boss mission, those 3 special ones with icons per map page), but a matter of how many tries will be needed to win and in consequence how many resources you will spend to win. The more powerfull your deck (plus some strong effects/artifacts against bosses) the cheaper it will be to win.

It's different from nomal missions in which your deck power (plus effects/artifacts) determine if you can win/pass a mission and with what chance (for either 1, 2 or 3 stars) you can do it. It's only worth investing to beat a boss if your deck can pass the following normal missions. In your case, you gotta know if your deck can win missions 81 to 85. I recomend using Combat Simulator. It's not perfect as it does not support all effects/artifacts, but it's a great tool and it will give a good estimate of how many tries will be needed to win against the boss and your chances on the normal missions.

Also, I would sugest to have a look on the previous events results, specialy the most recent ones to have an idea of endgame values and see if you can get there. If it is too far from what you can get, you will be wasting resources and will get out of top 250 anyway in the end.